Tips from gaining health

A pair of University of Colorado Cancer Center studies published this month show that the milk thistle extract, silibinin, kills skin cells mutated by UVA radiation and protects against damage by UVB radiation – thus protecting against UV-induced skin cancer and photo-aging.

“When you have a cell affected by UV radiation, you either want to repair it or kill it so that it cannot go on to cause cancer. We show that silibinin does both,” says Rajesh Agarwal, PhD, co-program leader of Cancer Prevention and Control at the CU Cancer Center and professor at the Skaggs School of Pharmacy and Pharmaceutical Sciences.

The first study, published in the journal Photochemistry and Photobiology worked with human skin cells subjected to UVA radiation, which makes up about 95 percent of the sun’s radiation that reaches Earth. The Agarwal Lab treated these UVA-affected cells with silibinin. With silibinin, the rate at which these damaged cells died increased dramatically.

“When you take human skin cells – keratinocytes – and treat them with silibinin, nothing happens. It’s not toxic. But when you damage these cells with UVA radiation, treatment with silibinin kills the cells,” Agarwal says, thus removing the mutated cells that can cause skin cancer and photo-aging.

Specifically, the study shows that pretreatment with silibinin resulted in higher release of reactive oxygen species (ROS) within the UVA-exposed cells, leading to higher rates of cell death.

The second study, published this month by the same authors in the journal Molecular Carcinogenesis shows that instead of beneficially killing cells damaged by UVA radiation, treatment with silibinin protects human skill cells from damage by UVB radiation, which makes up about 5 percent of the sun’s radiation reaching Earth.

Again, remember Agarwal’s suggestion that the prevention of UV-induced skin cancer can happen in two ways: by protecting against DNA damage or by killing cells with damaged DNA. With UVA, silibinin kills; with UVB, it protects, in this case by increasing cells’ expression of the protein interleukin-12, which works to quickly repair damaged cells.

“It has been 20 years of work with this compound, silibinin,” Agarwal says. “We first noticed its effectiveness in treating both skin and solid cancers, and we now have a much more complete picture of the mechanisms that allow this compound to work.”

Agarwal and colleagues continue to test the effectiveness of silibinin in cancer prevention and treatment in cell lines and mouse models, and are working toward human trials of silibinin-based therapeutics.

It seemed no one doubts the value of nutrients contained in milk. Milk is a source of protein, fats, vitamins, and minerals need to be consumed to meet the nutritional needs of the family. However, the milk becomes inadequate food consumption if not handled properly.




Currently on the market are available a variety of dairy products, some in the form of powder, condensed milk, or fresh milk. However, the sweetened condensed milk is not too recommended for daily consumption because of high sugar content.
Fresh milk, according to Dr. Samuel Oetoro, SpGK from Clover Clinic, have advantages over sweetened condensed milk or milk powder for the treatment process so that no excessive nutrients less wastage.
"Fresh milk, both in-pasteurized milk or UHT (ultrahigh temperature), both have the advantage of high nutritional value. Addition, the milk is ready to drink milk flavor more pronounced," he said.
While milk powder, a liquid milk processing process is dried, according to Dr. Samuel, will lose some nutrients. "Indeed, in this day and age supplemented milk powder, nutrients lost in processing will be added again. However, if you want to choose a natural, of course, the choice of fresh milk," he said.
However, powdered milk has the advantage of durability and practical because its easy to carry. In the meantime, if you prefer fresh milk directly purchased from a breeder, Dr. Samuel reminded the importance of seeking a safe source of milk.
"Although it is natural, but select farms that maintain the quality of its products. Consider whether the animal food that contain contaminants or do not," he said.

Prevent Trittle Bones - The calcium in milk is one of the bets nutrient for keeping bone health, because the calcium more easy absorbed by body. For getting maximal result, Milk should be drunk at night.

According to the nutritionist from the Department of Nutritional Sciences Faculty of Medicine, University of Indonesia (Faculty of medicine) dr.Fiastuti Witjaksono, Sp.GK, on the night of osteoclasts or cells of the bone crusher does not work.

"At night we also do not much activity, so that the calcium of milk absorbed optimally,"

he said in a celebration 10 Years of Partnership Residents Association Bones Healthy Indonesia (Perwatusi) with Anlene Wednesday (07/27/2011) in Jakarta.

Bone is living tissue that is active, so growing a young age and have the ability to repair when damaged or broken. This repair process occurs in the bone surface simultaneously. This special bone cells called osteoclasts that absorbed by bones that have been older, then osteoblasts to replace it with a new one.

After menopause, osteoclasts still absorb and destroy the collagen in bone mineral. However, the osteoblasts become slow work because of lack of estrogen. Thats why women at menopause prone to suffer from osteoporosis.

According Fiastuti, vitamin D and calcium, should be satisfied since a young age, because bone density reaches its peak at age 30.

"Bone density decreased with age. At the age of 30 years the speed of the process of bone destruction is greater than the speed of the process of bone loss,"

he explained.

Donkey Milk Lowering the Cholesterol | Cows milk, goat milk, or soy milk may have been commonly consumed. So, how about donkey milk, the experts said that donkey milk more nutrient then cows milk. Donkey milk also just have a little of fat.
Researchers from the University of Naples, Italy, doing a comparison between the donkeys milk and cow milk. As a result, the donkeys milk contains less fat and contain omega-3 fatty acids can help lower cholesterol.

In research that done at experiment animals, knew that animal gave the donkey milk have fats levels of triglycerides blood lower, and the metabolism system not stress.

Levels of triglycerides and high cholesterol, a precursor to narrowing of the arteries so that blood flow congestion. This condition can trigger heart attacks and strokes.

The researchers also found that donkey milk contains high calcium, similar to breast milk, and can be used in children who are allergic to cows milk.