Showing posts with label against. Show all posts
Showing posts with label against. Show all posts
Thursday, March 27, 2014
Silibinin found in milk thistle protects against UV induced skin cancer
A pair of University of Colorado Cancer Center studies published this month show that the milk thistle extract, silibinin, kills skin cells mutated by UVA radiation and protects against damage by UVB radiation – thus protecting against UV-induced skin cancer and photo-aging.
“When you have a cell affected by UV radiation, you either want to repair it or kill it so that it cannot go on to cause cancer. We show that silibinin does both,” says Rajesh Agarwal, PhD, co-program leader of Cancer Prevention and Control at the CU Cancer Center and professor at the Skaggs School of Pharmacy and Pharmaceutical Sciences.
The first study, published in the journal Photochemistry and Photobiology worked with human skin cells subjected to UVA radiation, which makes up about 95 percent of the sun’s radiation that reaches Earth. The Agarwal Lab treated these UVA-affected cells with silibinin. With silibinin, the rate at which these damaged cells died increased dramatically.
“When you take human skin cells – keratinocytes – and treat them with silibinin, nothing happens. It’s not toxic. But when you damage these cells with UVA radiation, treatment with silibinin kills the cells,” Agarwal says, thus removing the mutated cells that can cause skin cancer and photo-aging.
Specifically, the study shows that pretreatment with silibinin resulted in higher release of reactive oxygen species (ROS) within the UVA-exposed cells, leading to higher rates of cell death.
The second study, published this month by the same authors in the journal Molecular Carcinogenesis shows that instead of beneficially killing cells damaged by UVA radiation, treatment with silibinin protects human skill cells from damage by UVB radiation, which makes up about 5 percent of the sun’s radiation reaching Earth.
Again, remember Agarwal’s suggestion that the prevention of UV-induced skin cancer can happen in two ways: by protecting against DNA damage or by killing cells with damaged DNA. With UVA, silibinin kills; with UVB, it protects, in this case by increasing cells’ expression of the protein interleukin-12, which works to quickly repair damaged cells.
“It has been 20 years of work with this compound, silibinin,” Agarwal says. “We first noticed its effectiveness in treating both skin and solid cancers, and we now have a much more complete picture of the mechanisms that allow this compound to work.”
Agarwal and colleagues continue to test the effectiveness of silibinin in cancer prevention and treatment in cell lines and mouse models, and are working toward human trials of silibinin-based therapeutics.
Saturday, February 15, 2014
Young mango the acid is effective against constipation
Young mango, the acid is effective against constipation - Mango as we know is a very delicious delicious fruit. Not only the ripe mango, mango is also popular with many young people. Although a very sour taste, the fruit is still popular and always enjoyed as a complement to the fruit salad. On the other hand, young mango comes with a number of health benefits. go, peep efficacy young mango, reported Magforwomen.
1. Rich in vitamin C
Although sour taste, this fruit contains a lot of vitamin C which helps to meet the needs of the bodys calcium that makes bones strong. This important nutrient helps the body to fight inflammation. Blood vessels become stronger and more elastic. Vitamin C helps in the creation of new blood cells, iron uptake and prevention of bleeding.
2. Good for morning sickness
Pregnant women can eat to help calm the young mango minimize the intensity and frequency of morning sickness. You will see the loss of morning sickness after eating a regular young mango.
3. Remedy for indigestion and constipation
Young mango is rich in fiber, which helps in the treatment of constipation. Mix it with a little honey and salt will help to ward off indigestion.
4. Good for the heart
This fruit contains a large amount of iron. Young mango preserve liver function in order to stay healthy. Regular intake of young mango with a dose sufficient to reduce the risk of liver disease as it accelerates the secretion of bile acids and cleaning the intestines from bacterial infection.
5. Enhance disease resistance
Young mango helps the body to increase immunity and resistance against a number of diseases such as tuberculosis, anemia, cholera, diarrhea, dysentery. As well as various forms of cancer and heart disease can be prevented by regular consumption of young mango.
Eating green mango is very beneficial. But not too much so as not to upset stomach.
Readmore...
1. Rich in vitamin C
Although sour taste, this fruit contains a lot of vitamin C which helps to meet the needs of the bodys calcium that makes bones strong. This important nutrient helps the body to fight inflammation. Blood vessels become stronger and more elastic. Vitamin C helps in the creation of new blood cells, iron uptake and prevention of bleeding.
2. Good for morning sickness
Pregnant women can eat to help calm the young mango minimize the intensity and frequency of morning sickness. You will see the loss of morning sickness after eating a regular young mango.
3. Remedy for indigestion and constipation
Young mango is rich in fiber, which helps in the treatment of constipation. Mix it with a little honey and salt will help to ward off indigestion.
4. Good for the heart
This fruit contains a large amount of iron. Young mango preserve liver function in order to stay healthy. Regular intake of young mango with a dose sufficient to reduce the risk of liver disease as it accelerates the secretion of bile acids and cleaning the intestines from bacterial infection.
5. Enhance disease resistance
Young mango helps the body to increase immunity and resistance against a number of diseases such as tuberculosis, anemia, cholera, diarrhea, dysentery. As well as various forms of cancer and heart disease can be prevented by regular consumption of young mango.
Eating green mango is very beneficial. But not too much so as not to upset stomach.
Saturday, November 16, 2013
Chocolate can protect against tooth decay
Health for human | Yesterday after I eat coklat.teman I say that chocolate is not good for oral health. finally I was curious and started looking for the truth about it ... until finally I found the information that turned out ... Chocolate can protect against tooth decay. Direct read more info okay.
Researchers have found that chocolate can prevent damage to the tooth. This was so successful in combating decay that scientists believe are several components that may one day be added to mouthwash or toothpaste.
The study, conducted by researchers at Osaka University in Japan found that parts of cocoa beans, the main ingredient of chocolate, thwart mouth bacteria and tooth decay.
They found that the skin of cocoa beans - the exterior of the bean which usually goes to waste in chocolate production - has anti-bacterial effect on the mouth and can fight effectively against plaque and other harmful agents.
Tooth decay occurs when bacteria in the mouth turns into acid, which damages the surface of the teeth and cause dental caries.
Japanese scientists have discovered that chocolate is less harmful than many other sweet foods, as antibacterial agents in cocoa beans offset high levels of sugar.
After three months, the study found that the rates with a high sugar diet had a 14 hole average compared with only six cavities for those who received skin cocoa beans in their diet.
The researchers now plan to test their findings in humans.
Speaking to the magazine New Scientist, Takashi Ooshima, from Osaka University, say their findings could lead to new treatments for tooth decay.
"It may be possible to use a mouthwash CBH extracts, or supplements for a toothpaste."
It could even be put back into the chocolate to make it better for the teeth, he said
"They certainly have an effect but good oral hygiene, rather than eating lots of chocolate, is the way to good healthy teeth."
A spokesman for the British Dental Association said: "If its true that chocolate does help reduce tooth decay and cavities that can only be a good thing, but you must remember that chocolate contains sugar.
"Our advice remains the same: if people want to eat candy and sweet drinks they should limit it, and visit the dentist regularly."
Readmore...
Researchers have found that chocolate can prevent damage to the tooth. This was so successful in combating decay that scientists believe are several components that may one day be added to mouthwash or toothpaste.
The study, conducted by researchers at Osaka University in Japan found that parts of cocoa beans, the main ingredient of chocolate, thwart mouth bacteria and tooth decay.
They found that the skin of cocoa beans - the exterior of the bean which usually goes to waste in chocolate production - has anti-bacterial effect on the mouth and can fight effectively against plaque and other harmful agents.
Tooth decay occurs when bacteria in the mouth turns into acid, which damages the surface of the teeth and cause dental caries.
Japanese scientists have discovered that chocolate is less harmful than many other sweet foods, as antibacterial agents in cocoa beans offset high levels of sugar.
After three months, the study found that the rates with a high sugar diet had a 14 hole average compared with only six cavities for those who received skin cocoa beans in their diet.
The researchers now plan to test their findings in humans.
Speaking to the magazine New Scientist, Takashi Ooshima, from Osaka University, say their findings could lead to new treatments for tooth decay.
"It may be possible to use a mouthwash CBH extracts, or supplements for a toothpaste."
It could even be put back into the chocolate to make it better for the teeth, he said
"They certainly have an effect but good oral hygiene, rather than eating lots of chocolate, is the way to good healthy teeth."
A spokesman for the British Dental Association said: "If its true that chocolate does help reduce tooth decay and cavities that can only be a good thing, but you must remember that chocolate contains sugar.
"Our advice remains the same: if people want to eat candy and sweet drinks they should limit it, and visit the dentist regularly."
Monday, October 21, 2013
Advanced Therapy Against Baldness
Advanced Therapy Against Baldness - The threat of baldness in men is greater than with women. Reduced hair piece by piece, which ends with baldness, certainly disturbing. Though now there has been no solution to overcome baldness, at least, there are some therapies being developed by experts.
Here are some therapies that can provide hope for men in the future:
1. Hair Cloning
Therapy is to double the amount of wear hair healthy hair follicles, and the results disseminated in the head which is usually faster bald or already bald. In this way the new hair may appear thicker and healthier.
Hair multiplication method is still in test phase and continue to be developed. However, a company in the UK, Intercytex, which develops cell therapies for baldness, last year announced that the second phase of the test has been successfully implanted. They predict this method can be used widely within the next five years.
2. Genetic Tests
About two of three men go bald as they enter their 60s. Still, a few men whose hair has begun to decrease since youth. According to experts, this is because basically everyone already has a certain genetic pattern. In the case of baldness, there are gene variants that have been identified will lead to baldness. Therefore, experts assess preventive measures can be done earlier if the identification of these genes has been performed.
deCODE Genetics, genetic research-based company, currently has developed a method of gene introduction. Through this method will each person can find out if he was bald or not inherited the gene. If proven there is a risk of baldness, preventive measures can be done immediately.
3. Natural regeneration
In a study of cell regeneration in rats, by accident by scientists from the University of Pennsylvania found that hair follicles can participate regenerate. This opens an opportunity for scientists to create a type of artificial proteins to stimulate hair follicle growth.
Unfortunately the process of research to be done is still very long before we can really get the hair that grows naturally in the skin of a bald head.
Readmore...
1. Hair Cloning
Therapy is to double the amount of wear hair healthy hair follicles, and the results disseminated in the head which is usually faster bald or already bald. In this way the new hair may appear thicker and healthier.
Hair multiplication method is still in test phase and continue to be developed. However, a company in the UK, Intercytex, which develops cell therapies for baldness, last year announced that the second phase of the test has been successfully implanted. They predict this method can be used widely within the next five years.
2. Genetic Tests
About two of three men go bald as they enter their 60s. Still, a few men whose hair has begun to decrease since youth. According to experts, this is because basically everyone already has a certain genetic pattern. In the case of baldness, there are gene variants that have been identified will lead to baldness. Therefore, experts assess preventive measures can be done earlier if the identification of these genes has been performed.
deCODE Genetics, genetic research-based company, currently has developed a method of gene introduction. Through this method will each person can find out if he was bald or not inherited the gene. If proven there is a risk of baldness, preventive measures can be done immediately.
3. Natural regeneration
In a study of cell regeneration in rats, by accident by scientists from the University of Pennsylvania found that hair follicles can participate regenerate. This opens an opportunity for scientists to create a type of artificial proteins to stimulate hair follicle growth.
Unfortunately the process of research to be done is still very long before we can really get the hair that grows naturally in the skin of a bald head.
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